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Dot Disconnect

In this issue of Bandwidth, Senior Fellow John Wohlstetter examines the proposals from the 9/11 Commission’s report, and provides strong arguments against typical privacy and civil liberties advocates’ concerns.

Out to Lunch at Treasury?

If the major departments of government were baseball teams, the Treasury Department would be the New York Yankees. Historically, from the time of Alexander Hamilton, most of the best and brightest in government were in Treasury. Treasury was viewed as the class act. Treasury officials were treated with the respect that officials of HUD (Housing and Urban Development) could only Read More ›

Wealth Creators vs. Protectors

A major reason the liberal elites so hate President Bush is the policies he pushes will reduce their power and influence. Sens. John Kerry and Edward Kennedy, Massachusetts Democrats, claim they are the protectors of the little guy and the middle class. Yet their proposals are designed to protect the elite like themselves who inherited rather than created wealth. Much Read More ›

Key Law Review Articles About Teaching Darwin, Design and the Origins Controversy

“Teaching the Origins Controversy: Science, Or Religion, Or Speech?” (PDF file) By: David K. DeWolf, Stephen C. Meyer, Mark Edward DeForrest Utah Law Review (2000): 39-110. “A Liberty Not Fully Evolved?: The Case of Rodney LeVake and the Right of Public School Teachers to Criticize Darwinism.”(PDF file) San Diego Law Review 39.4 (Nov/Dec 2002): 1311-1325. David DeWolf, John West, and Read More ›

Multidrug resistant bacteria inside a biofilm
Antibiotic resistant bacteria inside a biofilm, 3D illustration. Biofilm is a community of bacteria where they aquire antibiotic resistance and communicate with each other by quorum sensing molecules

Genetic Analysis of Coordinate Flagellar and Type III Regulatory Circuits in Pathogenic Bacteria

Abstract: The bacterial flagellum represents one of the best understood molecular machines. Comprised of 40 parts that self-assemble into a true rotary engine, the biochemistry and genetics of these systems has revealed an unanticipated complexity. An essential component to assembly is the subset of parts that function as a protein secretory pump to ensure and discriminate that the correct number of protein subunits and their order of secretion is precisely regulated during assembly. Of further interest is the recognition of late that a number of important plant and animal pathogens use a related protein secretory pump fused to a membrane-spanning needle-like syringe by which a subset of toxins can be injected into target host cells. Together, the flagellar and virulence protein pumps are referred to as Type III Secretion Systems (TTSS). The archetype for TTSS systems has been the pathogenic members of the genus Yersinia which includes the organism responsible for bubonic plague, Y. pestis. Our interest in the Yersinia centers on the coordinate genetic regulation between flagellum biosynthesis and virulence TTSS expression. Y. enterocolitica, for example operates three TTSSs (motility, Ysa, and Yop), but each is expressed under defined mutually exclusive conditions. Y. pestis has lost the ability to assemble flagella (the genes are present on the chromosome) and expresses only the Yop system at 37oC, mammalian temperature. Using a combination of microarray analysis, genetic fusions, and behaviors of specific engineered mutants, we demonstrate how environmental factors influence gene expression of these multigene families, where the influence is exerted within each system, and propose why segregating these systems is critical for the organism. Our model further offers an explanation as to why an important subset of human pathogens has lost motility during their histories. Read More ›
political-art-concept-idea-of-free-speech-freedom-of-expression-and-censored-surreal-painting-portrait-illustration-conceptual-artwork-illustration-stockpack-adobe-stock
Political art, Concept idea of free speech freedom of expression and censored, surreal painting, portrait illustration , conceptual artwork illustration
Image licensed via Adobe Stock

Faith has Positive Effect on Country

George W. Bush is a religious fanatic hell-bent on imposing his view of God’s will on the world. At least, that’s what some journalists and academics would have us believe, including University of Washington Professor David Domke (“With God as his co-pilot,” Aug. 22). Domke concedes that other presidents have invoked “civil religion” in speeches but he claims Bush “is Read More ›

Amicus Curiae Brief of Biologists and Georgia Scientists, in Support of Defendants

Introduction Amici curiae are scientists who live in the State of Georgia and throughout the United States. Each of the individual signatories to the brief has earned a science-related doctoral degree. Amici include tenured university professors, research scientists and scientists in private industry. Amici are all scientists who question Neo-Darwinian evolutionary theory (the modern Darwinian theory of evolution) from a Read More ›

California’s Other Senator

MY STATE of California now has three United States senators. No, we weren’t granted increased representation because we are the biggest state. Rather, New Jersey Democratic senator Jon Corzine just tried to boost California’s biotech sector by personally donating $100,000 to help pass Proposition 71, an initiative on the November ballot that would force Californians to borrow $3 billion over Read More ›

Death Plays the Name Game

ASSISTED SUICIDE/EUTHANASIA activists are sure a restless bunch. They never seem able to settle on the right terminology to convince people to support legalizing mercy killing. First, it was euthanasia, a perfectly fine word that had a meaning generally akin to today’s concept of hospice before being hijacked by the right-to-die crowd in the early 20th century. When “euthanasia” didn’t Read More ›

How to Find Osama

Having just finished reading the report of the September 11 commission, I was shocked; shocked to learn major U.S. government bureaucracies are incompetent. Washington being Washington, most of the solutions proposed revolved around reorganizing and creating more bureaucracies. It seems not to have occurred to anyone there are market solutions for many information problems the intelligence community faces. Two examples Read More ›