genetic mutations

Darwin-Devolves-Michael-Behe

Darwin Devolves

The scientist who has been dubbed the “Father of Intelligent Design” and author of the groundbreaking book Darwin’s Black Box contends that recent scientific discoveries further disprove Darwinism and strengthen the case for an intelligent creator. In his controversial bestseller Darwin’s Black Box, biochemist Michael Behe challenged Darwin’s theory of evolution, arguing that science itself has proven that intelligent design is a better Read More ›

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Model of a molecule
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Experimental Evolution, Loss-of-Function Mutations, and “the First Rule of Adaptive Evolution”

Adaptive evolution can cause a species to gain, lose, or modify a function; therefore, it is of basic interest to determine whether any of these modes dominates the evolutionary process under particular circumstances. Because mutation occurs at the molecular level, it is necessary to examine the molecular changes produced by the underlying mutation in order to assess whether a given adaptation is best considered as a gain, loss, or modification of function. Although that was once impossible, the advance of molecular biology in the past half century has made it feasible. In this paper, I review molecular changes underlying some adaptations, with a particular emphasis on evolutionary experiments with microbes conducted over the past four decades. I show that by far the most common adaptive changes seen in those examples are due to the loss or modification of a pre-existing molecular function, and I discuss the possible reasons for the prominence of such mutations.

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Response: Waiting Longer for Two Mutations

In the Abstract of their recent article, “Waiting for Two Mutations: With Applications to Regulatory Sequence Evolution and the Limits of Darwinian Evolution” (GENETICS 180: 1501–1509, 2008), Durrett and Schmidt write that one of their aims is “to expose flaws in some of Michael Behe’s arguments concerning mathematical limits to Darwinian evolution.” Their effort, however, is itself seriously flawed. They Read More ›

Deconstructing Dawkins

As Oxford professor and arch-evangelist of atheism Richard Dawkins continues his crusade against religion, we finally have the first book-length critique of The God Delusion: Alister McGrath and Joanna Collicutt McGrath’s The Dawkins Delusion?: Atheist Fundamentalism and the Denial of the Divine (InterVarsity Press). One could hardly think of a more contrasting figure to Dawkins or a better apologist for Read More ›

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MUTANT SHRIMP? — A Correction

In a press release issued by Discovery Institute on February 6, I stated that researchers at the University of California at San Diego (UCSD) had produced a mutant shrimp and exaggerated its significance to evolutionary biology. I was mistaken. No mutant shrimp were produced. Alan Gishlick of the National Center for Science Education (NCSE) was quick to point this out, Read More ›

U.C. San Diego Researchers Exaggerate Findings to Promote Evolutionary Theory

A mutant shrimp is being claimed as “a landmark in evolutionary biology” that proves Darwin’s critics wrong. But it’s nothing of the sort, says biologist Jonathan Wells. A research team headed by William McGinnis at the University of California at San Diego has reported discovering a DNA mutation that produces shrimp without hind legs. Their report is being published in Read More ›