Michael J. Behe

Senior Fellow, Center for Science and Culture

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Methinks New PNAS Paper Is Like a Weasel

A paper by Wilf and Ewens recently published online in the Proceedings of the National Academy of Sciences, titled “There’s plenty of time for evolution,” reads like a printed version of Groundhog Day — the classic movie where comedian Bill Murray keeps awakening to find it’s the same day again. The paper’s authors sniff at unnamed benighted folks who think there hasn’t been enough time for (Darwinian) evolution to build the complexity we see in life. Not so, they protest. Why, all one has to do to see the light is to use the right mathematical model: “After guessing each of the letters, we are told which (if any) of the guessed letters are correct, and then those letters are retained. The second round of guessing is applied only for the

The Edge of Evolution, as seen by Dave Ussery and BioLogos

In his next installment Professor Ussery complains that I wasn’t enthusiastic enough in my chapter “What Darwinism Can Do.” As an example of common descent I pointed to Baker’s yeast, for which there is good evidence that sometime in the past its genome duplicated. But I also noted that other yeasts with unduplicated genomes have done fine for themselves. The point was that gene or even whole genome duplication is not the powerful tool that Darwinists often claim. That point passed over Dave’s head. His main comment on the book’s next chapter, “What Darwinism Can’t Do” is to tell the reader to search PubMed for the words “cilium” and “evolution.” One gets lots of papers that contain both those words, he assures

Dave Ussery Ruminates about The Edge of Evolution

The first part of Professor Ussery’s review of The Edge of Evolution on the website BioLogos is mainly an exercise in throat clearing, where he describes his “philosophical and personal perspective,” notes that he and I agree on common descent, and correctly points out that my book concerns the mechanism of evolution. In the second installment Dave begins to show that he somehow just doesn’t get the big points of the book. In writing of the sickle cell and other antimalarial mutations which degrade the genome, I had said that they were “hurtful.” He misunderstands this, writing, “the example gives us is not a ‘good mutation.'” But the sickle cell and other antimalarial mutations most certainly are “good” mutations in a

BioLogos Voices Sing the Same Old Tune

I normally do not respond to criticisms and reviews of my work that are simply posted on the internet. Rather, I engage reviews, comments, and articles that appear in journals or prominent newspapers and magazines. The reason is that those printed venues usually ask noted scientists or philosophers to review books, so that they are very likely to contain the most pertinent and insightful comments. After all, if a book challenging Darwinian evolution is reviewed separately by the likes of Sean Carroll, Jerry Coyne, Michael Ruse, and Richard Dawkins, then the odds are good that they would have discovered any major errors, if such there be. However, if upon considering their criticisms, we see huffing and puffing instead of reasoned argument, or an attack on straw men instead of the actual

A Malodorous Argument for Darwinian Evolution

University of California evolutionary biologist John Avise has penned a book, Inside the Human Genome: A Case for Non-Intelligent Design, and gotten it published by a top academic publishing house, Oxford University Press. Avise, a member of the National Academy of Sciences, has for decades been a leading researcher in evolutionary and ecological genetics. He has written hundreds of research articles and over a dozen books. Clearly he has an impressive scientific mind. Which makes it all the more astonishing that his new book shows all the intellectual savvy of a typical late-night college dormroom bull session. As his subtitle announces, Avise is anxious to show that, despite the claims of certain renegade biochemists, the molecular features of the human genome discovered by science

Misusing Protistan Examples to Propagate Myths About Intelligent Design

The Journal of Eukaryotic Microbiology recently published several papers from a workshop sponsored by the International Society of Protistologists titled “Horizontal Gene Transfer and Phylogenetic Evolution Debunk Intelligent Design.” So here we have a respected scientific society, presumably planning a workshop months in advance, and finally laying out their considered case for why intelligent design fails. As you might imagine, I was most anxious to read about it. Unfortunately, rather than scholarly papers, the manuscripts read like press releases from the National Center for (Darwinian) Science Education. So the introductory essay1 by Avelina Espinosa tells us that ID has “creationist beginnings,” claims that I say “evolution” is

God, Design, and Contingency in Nature

I recently received an email asking if the correspondent correctly understood my views about intelligent design and God. Since I sometimes get similar questions, I’m posting this correspondence for anyone who is interested. Q: I understand your current position to be that design is detectable in nature, and that design detection is not merely a theological gloss upon the scientific facts, but is actually an activity appropriate for science. I further understand you to be saying that design detection in itself is neutral regarding the way that the design found its way into nature. Thus, if the bacterial flagellum is designed, it *could* be that God took a regular bacterium and miraculously “tweaked” it, or it *could* be that God “front-loaded” the evolutionary

Probability and Controversy: Response to Carl Zimmer and Joseph Thornton

The science writer Carl Zimmer posted an invited reply on his blog from Joseph Thornton of the University of Oregon to my recent comments about Thornton’s work. This is the last of four posts addressing it. References appear at the bottom of this post. At the end of his post Thornton waxes wroth. Behe’s argument has no scientific merit. It is based on a misunderstanding of the fundamental processes of molecular evolution and a failure to appreciate the nature of probability itself. There is no scientific controversy about whether natural processes can drive the evolution of complex proteins. The work of my research group should not be misintepreted by those who would like to pretend that there is. Well, now. I’ll leave it to the reader of my previous replies to

Severe Limits to Darwinian Evolution: Response to Carl Zimmer and Joseph Thornton

The science writer Carl Zimmer posted an invited reply on his blog from Joseph Thornton of the University of Oregon to my recent comments about Thornton’s work. This is the third of several posts addressing it. References will appear in the last post. Now back to Thornton’s first point, the role of neutral mutations (which he sometimes labels “permissive” mutations). At several places in his post Thornton implies I’m unaware of the possibilities opened up by genetic drift: Behe’s discussion of our 2009 paper in Nature is a gross misreading because it ignores the importance of neutral pathways in protein evolution…. Behe’s first error is to ignore the fact that adaptive combinations of mutations can and do evolve by pathways involving

Not So Many Pathways: Response to Carl Zimmer and Joseph Thornton

The science writer Carl Zimmer posted an invited reply on his blog from Joseph Thornton of the University of Oregon to my recent comments about Thornton’s work. This is the second of several posts addressing it. References will appear in the last post.Now to Professor Thornton’s reply. He writes at length but makes just two substantive points: 1) that neutral mutations occur and can serendipitously help a protein evolve some function (“ ignores the key role of genetic drift in evolution”); and 2) that just because a protein may not be able to evolve a particular function one way does not mean that it, or some other kind of protein, can’t evolve the function another way (“nothing in our results implies that, if selection were to favor the ancestral

Piddling Pebbles and Empty Promises: Response to Carl Zimmer and Joseph Thornton

The science writer Carl Zimmer posted an invited reply on his blog from Joseph Thornton of the University of Oregon to my recent comments about Thornton’s work. This is the first of several posts addressing it. References will appear in the last post. I must say, it never ceases to amaze me how otherwise-very-smart folks like Zimmer and Thornton fail to grasp pretty simple points when it comes to problems for Darwinian mechanisms. Let me start slowly with a petty complaint in Carl Zimmer’s intro to the post. Zimmer is annoyed that I think Thornton’s latest work is “great,” yet I thought his previous work published a few years ago was “piddling.” “Why the change of heart?” wonders Zimmer. It’s really not that hard to understand.

New Work by Richard Lenski

A new paper from Richard Lenski’s group has appeared in Nature and has garnered a fair amount of press attention. Some people asked me for my thoughts about it. The new paper continues the grand experiment that Lenski has been publishing about lo these many years — allowing a culture of the bacterium E. coli to continuously grow and evolve under his close observation. The only really new thing reported is a technical improvement — these days one can have the entire genome of E. coli “re-sequenced” (that is, determine the sequence of the entire DNA of the particular E. coli you’re working with) done for an affordable cost. (There are companies which will do it for a fee.) So Lenski and collaborators had the whole genomes — each and every

Dollo’s law, the symmetry of time, and the edge of evolution

Nature has recently published an interesting paper which places severe limits on Darwinian evolution. The manuscript, from the laboratory of Joseph Thornton at the University of Oregon, is titled “An epistatic ratchet constrains the direction of glucocorticoid receptor evolution”. The work is interpreted by its authors within a standard Darwinian framework, but the results line up very well with arguments I made in The Edge of Evolution. This is the last of three posts discussing it. (see here and here) Bridgham et al (2009) are interested in the reversibility of evolution, and discuss their results in terms of something called “Dollo’s law.” Louis Dollo, an early 20th century paleobiologist, was interested in discerning phylogenies. He maintained that one

Nature Paper Reaches “Edge of Evolution” and Finds Darwinian Processes Lacking

Nature has recently published an interesting paper which places severe limits on Darwinian evolution. The manuscript, from the laboratory of Joseph Thornton at the University of Oregon, is titled, “An epistatic ratchet constrains the direction of glucocorticoid receptor evolution.” The work is interpreted by its authors within a standard Darwinian framework, but the results line up very well with arguments I made in The Edge of Evolution. This is the second of several posts discussing it. Using clever synthetic and analytical techniques, Bridgham et al (2009) show that the more recent hormone receptor protein that they synthesized, a GR-like protein, can’t easily revert to the ancestral structure and activity of an MR-like protein because its structure has been

Nature Publishes Paper on the Edge of Evolution

Nature has published an interesting paper recently which places severe limits on Darwinian evolution. This is the first of several posts discussing it. The manuscript, from the laboratory of Joseph Thornton at the University of Oregon, is titled “An epistatic ratchet constrains the direction of glucocorticoid receptor evolution.” The work is interpreted by its authors within a standard Darwinian framework. Nonetheless, like the important work over the years of Michigan State’s Richard Lenski on laboratory evolution of E. coli, which has shown trillions of bacteria evolving under selection for tens of thousands of generations yielding just broken genes and minor changes, the new work demonstrates the looming brick wall which confronts unguided evolution in at least

Bloggingheads Explains

In a new segment, Bloggingheads chief Robert Wright and Bloggingheads correspondent George Johnson go on for 75 minutes about the trauma of a pair of heretics (me and Paul Nelson, on separate segments) appearing on their site. I would urge everyone who doesn’t have pressing matters to attend to, such as the need to wash your hair, to tune in for the full time. It’s really fascinating in its way to see two grown men in such a hand-wringing lather. It’s also fascinating to see that neither of them in 75 minutes offers a reason for the correctness of their own views, or the wrongness of ours. The closest they come is when George Johnson invokes the hoary “methodological naturalism.” One little segment was particularly rich. Johnson is faint with

Reducible Versus Irreducible Systems and Darwinian Versus Non-Darwinian Processes

Recently a paper appeared online in the journal Proceedings of the National Academy of Sciences, entitled “The reducible complexity of a mitochondrial molecular machine.” As you might expect, I was very interested in reading what the authors had to say. Unfortunately, as is all too common on this topic, the claims made in the paper far surpassed the data, and distinctions between such basic ideas as “reducible” versus “irreducible” and “Darwinian” versus “non-Darwinian” were pretty much ignored. Since PNAS publishes letters to the editor on its website, I wrote in. Alas, it seems that polite comments by a person whose work is the clear target of the paper are not as welcome as one might suppose from reading the

Behe: Back on Bloggingheads TV

The editor-in-chief of Bloggingheads TV, Robert Wright, has re-instated my interview with linguist John McWhorter on that website. Wright was away last week when the brouhaha occurred. It’s good to see that a steady editorial hand is back in

Bloggingheads TV and Me

I’ve just been through the weirdest book-related experience I’ve had since a Canadian university professor with a loaded rat trap chased me around after a talk I gave a dozen years ago, threatening to spring it on me. Last week I got the following email bearing the title “Invitation to Appear on Bloggingheads TV” from a senior editor at that site: Hi, Michael– I’d like to invite you to appear on Bloggingheads.tv, a web site that hosts video dialogues between journalists, bloggers, and scholars. We have a partnership with the New York Times by which they feature excerpts from some of our shows on their site. Past guests include prominent thinkers such as Paul Krugman, Paul Ehrlich, Frans de Waal, David Frum, Richard Wrangham, Francis Fukuyama,

What Michael Behe actually wrote in TIME

TIME Magazine asked me to write an entry on Richard Dawkins for “The TIME 100” this year. After their editing, it came out rather more insipid than I wrote it. They asked for 400-500 words, but pared it down to 187 — and that’s after adding their own phrases (e.g., “deeply unsettling to proponents of intelligent design,” “the rigor he brings to his thinking,” “the Bible advises us,” etc.)! The entry, as I originally wrote it, follows below: Of his nine books, none caused as much controversy — or sold as well — as last year’s The God Delusion. Yet the leading light of the recent atheist publishing surge, Oxford University’s Richard Dawkins, has always been a man driven by the big questions. Born in Kenya in 1941