On this episode of ID the Future, biochemist Michael Behe and host Andrew McDiarmid discuss the anti-malarial drug chloroquine, now being investigated as a treatment for COVID-19, and how it may work on the cellular level against the coronavirus. The same drug was featured in Behe’s 2007 book The Edge of Evolution, as part of his demonstration that evolution has strict limits: It can do adaptive work for organisms with single mutations, but if just two coordinated mutations are required at once, evolution’s random processes have great difficulty even with natural selection helping them along. In cases where population sizes are enormous, as with malaria, it can eventually overcome the need for two simultaneous and coordinated mutations, but only just barely. Because the odds go up exponentially, three simultaneous coordinated mutations may be beyond the edge of evolution. What does all this bode for chloroquine and the coronavirus? Listen in as McDiarmid and Behe discuss.
On this episode of ID the Future, guest host Jonathan Witt sits down with molecular biologist Douglas Axe at the recent Dallas Science and Faith Conference. Axe, author of Undeniable: How Biology Confirms Our Intuition That Life Is Designed, had his research on protein folds published in the Journal of Molecular Biology, work showing that random mutations are not up to the task of building fundamentally new protein folds from old, a finding that poses a major challenge to modern evolutionary theory. After all, if evolution can’t build something as basic as a new protein fold, how could it build whole new organs and body plans in the history of life? But Witt presents Axe with an objection: Axe couldn’t possibly have tested more than the tiniest fraction of a fraction of all the possible amino acid combinations for the protein he studied, so how can we trust his findings? Tune in to hear Axe’s explanation, and to learn about other lines of evidence confirming his research.
On this episode of ID the Future, Dr. Michael Behe talks with Casey Luskin about recent findings that support his argument in The Edge of Evolution. Dr. Behe explains why Chloroquine, a drug that treats malaria, presents a good opportunity to study the limits of random mutation and natural selection, and how his conclusions inspired so much backlash–including misrepresentation of his argument–from his critics.