{"id":10504,"date":"2024-05-01T20:58:03","date_gmt":"2024-05-01T20:58:03","guid":{"rendered":"https:\/\/www.discovery.org\/id\/?page_id=10504"},"modified":"2026-06-05T22:02:07","modified_gmt":"2026-06-05T22:02:07","slug":"research","status":"publish","type":"page","link":"https:\/\/www.discovery.org\/id\/research\/","title":{"rendered":"Research Program"},"content":{"rendered":"\n<div class=\"wp-block-cover m-b-n\"><img loading=\"lazy\" decoding=\"async\" width=\"1456\" height=\"816\" class=\"wp-block-cover__image-background wp-image-10510\" alt=\"\" src=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/04\/studet-lab-copy.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/04\/studet-lab-copy.jpg 1456w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/04\/studet-lab-copy-1000x560.jpg 1000w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/04\/studet-lab-copy-768x430.jpg 768w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/04\/studet-lab-copy-50x28.jpg 50w\" sizes=\"auto, (max-width: 1456px) 100vw, 1456px\" \/><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\"><\/span><div class=\"wp-block-cover__inner-container is-layout-constrained wp-block-cover-is-layout-constrained\">\n<h1 class=\"wp-block-heading has-text-align-center\">ID 3.0 Research Program<\/h1>\n<\/div><\/div>\n\n\n\n<section class=\"wp-block-signal-section introduction constrain-md\">\n<p class=\"wp-block-paragraph\">Discovery Institute\u2019s Science Research Program entails a vibrant community of scientists and scholars who are conducting scientific research to investigate the evidence for design in nature, and also research that critically investigates the ability of material mechanisms to account for the complexity of nature. Much of this research is directly funded by Discovery Institute, while other research is conducted by a network of ID-friendly scientists that Discovery Institute actively collaborates with and sustains.<\/p>\n<\/section>\n\n\n\n<figure class=\"wp-block-table constrain-lg has-medium-font-size\"><table><tbody><tr><td class=\"has-text-align-center\" data-align=\"center\"><strong>25+ <a class=\"ek-link\" href=\"#highlights\">Active Research Projects<\/a><\/strong><\/td><td class=\"has-text-align-center\" data-align=\"center\"><strong>250+ <a href=\"https:\/\/www.discovery.org\/id\/peer-review\/\" class=\"ek-link\">Peer-Reviewed Papers<\/a><\/strong><\/td><td><strong>$10+ million total budget since 2016<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<section class=\"wp-block-signal-section phases details-stack constrain-md\">\n<div class=\"wp-block-cover has-custom-content-position is-position-bottom-center m-tb-n\" style=\"min-height:200px;aspect-ratio:unset;\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1707\" class=\"wp-block-cover__image-background wp-image-10633\" alt=\"\" src=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/dna-strands-as599971433-scaled.jpeg\" data-object-fit=\"cover\" srcset=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/dna-strands-as599971433-scaled.jpeg 2560w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/dna-strands-as599971433-1000x667.jpeg 1000w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/dna-strands-as599971433-1600x1067.jpeg 1600w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/dna-strands-as599971433-768x512.jpeg 768w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/dna-strands-as599971433-1536x1024.jpeg 1536w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/dna-strands-as599971433-2048x1365.jpeg 2048w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/dna-strands-as599971433-50x33.jpeg 50w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/dna-strands-as599971433-600x400.jpeg 600w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\" style=\"background-color:#4d5d75\"><\/span><div class=\"wp-block-cover__inner-container is-layout-constrained wp-block-cover-is-layout-constrained\">\n<header class=\"wp-block-signal-header\">\n<h2 class=\"wp-block-heading\" id=\"threepointo\">ID 3.0 Research<\/h2>\n<\/header>\n<\/div><\/div>\n\n\n\n<center class=\"wp-block-signal-center\">\n<p class=\"wp-block-paragraph\">Intelligent design is a potent scientific theory which makes testable predictions that are being actively investigated by researchers worldwide. The ID 3.0 research program comprises this community of scientists who have collaborated to publish peer-reviewed scientific papers related to the evidence for design in prominent journals, including&nbsp;<em>Nature<\/em>,&nbsp;<em>ACS Nano<\/em>,&nbsp;<em>ACS Applied Materials &amp; Interfaces<\/em>,&nbsp;<em>Nature Nanotechnology<\/em>,&nbsp;<em>Journal of Bacteriology<\/em>,&nbsp;<em>Scientific Reports<\/em>,&nbsp;<em>Frontiers in Microbiology<\/em>,&nbsp;<em>Frontiers in Genetics<\/em>,&nbsp;<em>Annual Review of Genomics and Human Genetics<\/em>,&nbsp;<em>Biosystems<\/em>,&nbsp;<em>BMC Evolutionary Biology<\/em>,&nbsp;<em>BMC Genomics<\/em>,&nbsp;<em>Molecular Biology and Evolution<\/em>,&nbsp;<em>BIO-Complexity<\/em>,&nbsp;<em>Springer Proceedings in Mathematics and Statistics<\/em>,&nbsp;<em>PLOS One<\/em>,&nbsp;<em>Journal of Theoretical Biology<\/em>, and a book with Cambridge University Press, among other technical outlets.<\/p>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\">\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1600\" height=\"1067\" data-id=\"10702\" src=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/biola-gunasekera-axe-may24-26-1600x1067.jpg\" alt=\"\" class=\"wp-image-10702\" srcset=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/biola-gunasekera-axe-may24-26-1600x1067.jpg 1600w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/biola-gunasekera-axe-may24-26-1000x667.jpg 1000w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/biola-gunasekera-axe-may24-26-768x512.jpg 768w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/biola-gunasekera-axe-may24-26-1536x1024.jpg 1536w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/biola-gunasekera-axe-may24-26-2048x1365.jpg 2048w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/biola-gunasekera-axe-may24-26-50x33.jpg 50w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/biola-gunasekera-axe-may24-26-600x400.jpg 600w\" sizes=\"auto, (max-width: 1600px) 100vw, 1600px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" data-id=\"10698\" src=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/biola_veritas_creative_agency_may24-40-1600x1067.jpg\" alt=\"\" class=\"wp-image-10698\"\/><\/figure>\n<figcaption class=\"blocks-gallery-caption wp-element-caption\"><sup>Professors Doug Axe and Richard Gunasekera in their biochemistry lab at Biola University.<\/sup><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">ID research has gone through multiple phases, roughly described below.&nbsp;<\/p>\n\n\n\n<details class=\"wp-block-signal-details id-1\"><summary>ID 1.0 (1984-1999)<\/summary><center>\n<p class=\"wp-block-paragraph\">This first phase of ID research developed basic theories of design detection via information, including concepts like irreducible complexity, specified complexity, and the explanatory filter.<\/p>\n\n\n\n<ul class=\"wp-block-list dotted-lines m-t-0\">\n<li>B<span style=\"font-size: revert;\">ooks include&nbsp;<\/span><em style=\"font-size: revert;\">The Mystery of Life&#8217;s Origins<\/em><span style=\"font-size: revert;\">,&nbsp;<\/span><em style=\"font-size: revert;\">Darwin&#8217;s Black Box<\/em><span style=\"font-size: revert;\">, and&nbsp;<\/span><em style=\"font-size: revert;\">The Design Inference<\/em><span style=\"font-size: revert;\">.<\/span><\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details id-2\"><summary>ID 2.0 (2000-2015)<\/summary><center>\n<p class=\"wp-block-paragraph\">The second phase of ID research began to experimentally apply the methods of design-detection developed in ID 1.0 to real-world systems. The focus was studying protein evolvability, while theorists furthered the positive case for design by showing the superior explanatory ability of design via inferences to the best explanation. ID-oriented labs also emerged such as Biologic Institute and Evolutionary Informatics Lab. The latter made important theoretical progress showing that new complex and specified information can only be produced by intelligent agency.&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list dotted-lines m-t-0\">\n<li>Over 75 peer-reviewed publications in journals such as&nbsp;<em>Protein Science<\/em>,&nbsp;<em>Journal of Molecular Biology<\/em>,&nbsp;<em>Theoretical Biology and Medical Modelling<\/em>,&nbsp;<em>BIO-Complexity<\/em>,&nbsp;<em>Journal of Advanced Computational Intelligence and Intelligent Informatics<\/em>,&nbsp;<em>Complexity<\/em>,&nbsp;<em>Quarterly Review of Biology<\/em>,&nbsp;<em>Rivista di Biologia \/ Biology Forum<\/em>,&nbsp;<em>Physics of Life Reviews<\/em>, and&nbsp;<em>Annual Review of Genetics<\/em>.<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details id-3\"><summary>ID 3.0 (2016-present)<\/summary><center>\n<p class=\"wp-block-paragraph\">The third and current phase of ID research extends ID 2.0 to new systems and fields, showing the heuristic value of intelligent design to guide scientific research. This research includes not only testing the origin of new systems, but also using ID to answer questions and make novel contributions in burgeoning fields, such as epigenetics, synthetic biology, systems biology, genomics (e.g., investigating function for junk DNA), systematics and phylogenetics, information theory, population genetics, biological fine-tuning, molecular machines, ontogenetic information, paleontology, quantum cosmology, cosmic fine-tuning, astrobiology, local fine-tuning, and many others.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Under ID 3.0 there is a special emphasis on unexpected features of the genome which reveal new layers of biological information and control. In addition to interpreting pre-existing data within an ID framework, we are generating new data and asking questions that ID prompts \u2014 and potentially answers.<\/p>\n\n\n\n<ul class=\"wp-block-list dotted-lines m-t-0\">\n<li>Over 100 ID 3.0-related peer-reviewed papers published since 2016 in journals such as <em>Journal of Bacteriology<\/em>, <em>Systems Engineering<\/em>, <em>BIO-Complexity<\/em>, <em>PLOS One<\/em>, <em>Biomimetics<\/em>, <em>Journal of Organic Chemistry<\/em>, <em>Science Advances<\/em>, <em>ACS Omega<\/em>, <em>EC Pharmacology and Toxicology<\/em>, <em>ACS Applied Materials &amp; Interfaces<\/em>, <em>ACS Nano, Nature<\/em>, <em>Journal of Neurosurgery: Pediatrics<\/em>, <em>Journal of Theoretical Biology<\/em>.&nbsp;<\/li>\n<\/ul>\n<\/center><\/details>\n<\/center>\n<\/section>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity constrain-lg research-divider display-none\"\/>\n\n\n\n<section class=\"wp-block-signal-section types details-stack constrain-md\">\n<div class=\"wp-block-cover is-light has-custom-content-position is-position-bottom-center m-tb-n has-white-color has-text-color has-link-color wp-elements-1\" style=\"min-height:200px;aspect-ratio:unset;\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1435\" class=\"wp-block-cover__image-background wp-image-10635\" alt=\"A magnified image of a euglenoid cell highlighting its flagellum that enables it to swim and gather nutrients from its surroundings.\" src=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/euglenoid-cell-flagellum-scaled.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/euglenoid-cell-flagellum-scaled.jpg 2560w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/euglenoid-cell-flagellum-1000x560.jpg 1000w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/euglenoid-cell-flagellum-1600x897.jpg 1600w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/euglenoid-cell-flagellum-768x430.jpg 768w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/euglenoid-cell-flagellum-1536x861.jpg 1536w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/euglenoid-cell-flagellum-2048x1148.jpg 2048w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/euglenoid-cell-flagellum-50x28.jpg 50w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><small class=\"description toggler\"><span>Image licensed via Adobe Stock<\/span><\/small><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\" style=\"background-color:#918473\"><\/span><div class=\"wp-block-cover__inner-container is-layout-constrained wp-block-cover-is-layout-constrained\">\n<h2 class=\"wp-block-heading\" id=\"types\">Types of ID Research<\/h2>\n<\/div><\/div>\n\n\n\n<header class=\"wp-block-signal-header\"><\/header>\n\n\n\n<center class=\"wp-block-signal-center\">\n<p class=\"wp-block-paragraph\">As seen in the examples listed above, ID inspires new avenues of scientific research, and ID proponents do scientific research and have published hundreds of peer-reviewed scientific papers relevant to the evidence for design. The breadth and potency of ID research illustrates the fact that it can be divided into two general types \u2014 <strong>pure<\/strong> and <strong>applied<\/strong>.<\/p>\n\n\n\n<details class=\"wp-block-signal-details pure-research\"><summary><strong>Pure<\/strong> Intelligent Design Research<\/summary><center>\n<p class=\"wp-block-paragraph\">Having shown that many features of nature were designed, pure ID research allows us to make the reasonable conclusion that design is a useful model for understanding the natural world. This confidence in design theory allows us to then further assume design is prevalent, and based upon this assumption, apply design reasoning to explore new systems in the natural world.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Pure ID research&nbsp;<\/em>asks how we can detect design, and\/or investigates natural systems to determine whether design is the best explanation for the features we observe. Essentially, pure ID research aims to refine and employ design-detection methods to determine if a design inference is warranted for a given system or phenomenon we find in nature. Pure ID research has determined that many aspects of life, planet Earth, the solar system, the galaxy, and the universe display evidence of design.&nbsp;This kind of research might also involve critiquing naturalistic explanations as part of making a case for design.<\/p>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details applied-research\"><summary><strong>Applied<\/strong> Intelligent Design Research<\/summary><center>\n<p class=\"wp-block-paragraph\"><em>Applied ID research<\/em>&nbsp;uses the assumption of design to better understand how natural systems work. A few examples will help illustrate what this means:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Having shown that the genome is rich in complex and specified information, we might now assume that design is prevalent throughout the genome. This allows us to ask further questions, like whether the poorly understood \u201cdark matter\u201d of the genome (often called \u201cjunk DNA\u201d) might have important functions. Applied ID research is now predicting and discovering function for so-called \u201cjunk DNA.\u201d<\/li>\n\n\n\n<li>Having shown that organisms are integrated wholes that exhibit a form of designed irreducible complexity on the macroscale, we might then assume that design-based engineering principles were used throughout the blueprints of life. The assumption then opens up many new avenues of investigation into the operation of biological systems. For example, we might adopt a skeptical mindset towards claims that the human skeletal system is \u201cpoorly designed,\u201d and upon critically investigate those claims we discover new functions and reasons for the bones and joints that we have. Or, we might apply lessons learned from human technology to ask whether circuit control mechanisms from electrical engineering can help explain features of biology, such as gene regulation, cell-communication, or patterns of blood flow in the brain. Even evolutionary concepts such as adaptation may turn out to follow engineering principles where systems are preprogrammed to respond to inputs within designed tolerance limits.&nbsp;<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Applied ID research is thus making progress to help us better understand the workings of biological systems by applying the assumption of design to our investigations of the operations of nature.&nbsp;<\/p>\n<\/center><\/details>\n<\/center>\n<\/section>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity constrain-lg research-divider display-none\"\/>\n\n\n\n<section class=\"wp-block-signal-section highlights constrain-md\">\n<div class=\"wp-block-cover has-custom-content-position is-position-bottom-center m-tb-n\" style=\"min-height:200px;aspect-ratio:unset;\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1435\" class=\"wp-block-cover__image-background wp-image-10640\" alt=\"A depiction of lactic acid bacteria, a type of probiotic important for health\" src=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/lactic-acid-bacteria-scaled.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/lactic-acid-bacteria-scaled.jpg 2560w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/lactic-acid-bacteria-1000x560.jpg 1000w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/lactic-acid-bacteria-1600x897.jpg 1600w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/lactic-acid-bacteria-768x430.jpg 768w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/lactic-acid-bacteria-1536x861.jpg 1536w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/lactic-acid-bacteria-2048x1148.jpg 2048w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/lactic-acid-bacteria-50x28.jpg 50w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><small class=\"description toggler\"><span>Image licensed via Adobe Stock<\/span><\/small><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\" style=\"background-color:#3c7f9f\"><\/span><div class=\"wp-block-cover__inner-container is-layout-constrained wp-block-cover-is-layout-constrained\">\n<header class=\"wp-block-signal-header\">\n<h2 class=\"wp-block-heading\" id=\"highlights\">Highlights<\/h2>\n<\/header>\n<\/div><\/div>\n\n\n\n<center class=\"wp-block-signal-center details-stack\">\n<p class=\"wp-block-paragraph\">Below we highlight a partial list of ID 3.0 projects, researchers, as well as papers produced by those projects. Some ID 3.0 projects and researchers are not listed to protect the investigators from threats to their careers if it were publicly known they were doing ID-related research. Some papers for some projects are not listed for the same reasons. For a more complete list of peer-reviewed scientific paper supporting intelligent design, see&nbsp;<a href=\"https:\/\/www.discovery.org\/id\/peer-review\/\">Peer Reviewed Articles Supporting Intelligent Design<\/a>.&nbsp;<\/p>\n\n\n\n<details class=\"wp-block-signal-details bacterial-adaptation\"><summary>Bacterial Adaptation<\/summary><center>\n<p class=\"wp-block-paragraph\">Bacteria have short generation times and large population sizes, making them an ideal test case for the creative power of evolutionary mechanisms. This project, which spans multiple sub-projects, is testing the evolvability of new features in bacteria and other microorganisms through laboratory experiments and digital simulations. One project led by biologists Ann Gauger and Ralph Seelke (late professor of Biology and Earth Sciences at the University of Wisconsin-Superior) broke a gene in the bacterium&nbsp;<em>E. coli<\/em>&nbsp;required for synthesizing the amino acid tryptophan. When the bacteria\u2019s genome was broken in just one place, random mutations were capable of \u201cfixing\u201d the gene. But when just two mutations were required to restore function, Darwinian evolution became stuck, unable to restore the full function. Another project by Michael Behe reviewed numerous published examples of Darwinian evolution in bacteria and viruses, and found that adaptations at the molecular level \u201care due to the loss or modification of a pre-existing molecular function,\u201d showing that evolutionary mechanisms are far better at breaking features than building new ones. This principle was confirmed by another ID 3.0 project, published in the&nbsp;<em>Journal of Bacteriology<\/em>&nbsp;by Dusty van Hofwegen and Scott Minnich, which tested a widely touted bacterial innovation of Richard Lenski\u2019s \u201cLong-Term Evolution Experiment,\u201d and found it actually involved \u201cno new genetic information (novel gene function).\u201d Theoretical simulations confirm the inability of Darwinian mechanisms to produce new features. Douglas Axe has developed a simulation called&nbsp;<em>Stylus<\/em>, which not only models the evolution of new proteins (see the Protein Zoo project below), but also modeled the \u201clong-term evolution\u201d of a population of 1000 \u201cdigital organisms,\u201d and found that over time they experienced \u201cgenome decay\u201d \u2014 suggesting some factor must be inputting information to allow species to persist and evolve.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Selected Publications<\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li>Douglas D. Axe, Jireh Gerry, Alisa D. Daniels, Sabrina Wilkerson, William Mitchell, and Sarah Randall, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/view\/BIO-C.2023.2\">Fitness Decline Over Long-Term Evolution of a Small Population of Asexual Computational Organisms<\/a>,\u201d <em>BIO-Complexity<\/em>, 2023(2): 1-9 (2023).<\/li>\n\n\n\n<li>Dustin J. Van Hofwegen, Carolyn J. Hovde, Scott A. Minnich, \u201c<a href=\"https:\/\/journals.asm.org\/doi\/10.1128\/jb.00831-15\">Rapid Evolution of Citrate Utilization by <em>Escherichia coli<\/em> by Direct Selection Requires <em>citT <\/em>and <em>dctA<\/em><\/a>,\u201d <em>Journal of Bacteriology<\/em>, 198(7): 1022-1034 (April, 2016).<\/li>\n\n\n\n<li>Douglas D. Axe, Philip Lu, and Stephanie Flatau, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2011.3\">A Stylus-Generated Artificial Genome with Analogy to Minimal Bacterial Genomes<\/a>,\u201d <em>BIO-Complexity<\/em>, Vol. 2011 (3).<\/li>\n\n\n\n<li>Ann K. Gauger, Stephanie Ebnet, Pamela F. Fahey, and Ralph Seelke, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2010.2\">Reductive Evolution Can Prevent Populations from Taking Simple Adaptive Paths to High Fitness<\/a>,\u201d <em>BIO-Complexity<\/em>, 2010 (2): 1-9 (2010).<\/li>\n\n\n\n<li>Michael J. Behe, \u201c<a href=\"https:\/\/www.journals.uchicago.edu\/doi\/10.1086\/656902\">Experimental Evolution, Loss-of-Function Mutations and \u2018The First Rule of Adaptive Evolution\u2019<\/a>,\u201d <em>Quarterly Review of Biology<\/em>, 85(4): 419-445 (December, 2010).<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details brain-blood-flow\"><summary>Brain Blood Flow<\/summary><center>\n<p class=\"wp-block-paragraph\">Every time your heart beats it pulses blood into your brain. But if these pulses of blood flow aren\u2019t carefully controlled, they would burst the fragile, tightly organized capillaries throughout the brain. Applying the assumption that the brain is a \u201cdesigned system,\u201d Michael Egnor, a pediatric neurosurgeon and professor in the Department of Neurological Surgery at Stony Brook University, has sought to understand how our physiology allows blood to flow smoothly into and through the brain (Egnor 2019). By carefully measuring blood flow, Egnor and his team have found that brain capillary blood flow is controlled by a band stop filter, and cerebrospinal fluid flow is controlled by a band pass filter \u2014 revealing intelligent design in the brain. They have published papers in&nbsp;<em>BIO-Complexity<\/em>&nbsp;and the&nbsp;<em>Journal of Neurosurgery Pediatrics<\/em>, with ongoing work analyzing the data to assess the model of brain blood flow control.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Papers<\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li>Michael Egnor, Liu Yang, Racheed M. Mani, Susan M. Fiore, and Petar M. Djuri\u0107, \u201c<a href=\"https:\/\/thejns.org\/pediatrics\/view\/journals\/j-neurosurg-pediatr\/32\/3\/article-p302.xml\">A quantitative model of the cerebral windkessel and its relevance to disorders of intracranial dynamics<\/a>,\u201d&nbsp;<em>Journal of Neurosurgery: Pediatrics<\/em>, 32: 302-311 (Sept. 2023).<\/li>\n\n\n\n<li>Zhe Wang, Liu Yang, Petar M. Djuri\u0107, and Michael R. Egnor, \u201c<a href=\"https:\/\/thejns.org\/pediatrics\/view\/journals\/j-neurosurg-pediatr\/29\/6\/article-p719.xml\">Why don\u2019t ventricles dilate in pseudotumor cerebri? A circuit model of the cerebral windkessel<\/a>,\u201d&nbsp;<em>Journal of Neurosurgery: Pediatrics<\/em>, 29: 719-726 (2022).<\/li>\n\n\n\n<li>Michael Egnor, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2019.3\">The Cerebral Windkessel as a Dynamic Pulsation Absorber<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, 2019: 3 (2019).<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details killing-nanomachines\"><summary>Cancer and Bacteria-Killing Nanomachines<\/summary><center>\n<p class=\"wp-block-paragraph\">One of the largest and most successful ID 3.0 research project focuses on nanomachines and is led by one of the world\u2019s top organic chemists, Prof. James Tour at Rice University, as well as top collaborator Richard Gunasekera, a biologist who has worked with the University of Houston, Rice University, and now Biola University. Tour\u2019s project initially designed miniature nanocars \u2014 50,000 of which could fit on the width of a human hair \u2014 as a way of demonstrating new techniques for creating nanomachinery. While designing these machines Tour developed a novel critique of chemical evolutionary theory. Tour showed that designing even relatively simple nanomachines required a complex series of chemical manipulations and a well-choreographed chemical procedure. Since the design of his nanomachines required intelligent intervention at every stage, he argues that the origin of life, and the much more complex molecular machinery required for it, cannot currently be plausibly explained by undirected chemical processes alone.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Tour subsequently applied the techniques he had developed in the design of his nanocars to design another molecular machine \u2014 a \u201cnano-augur\u201d or \u201cnanodrill\u201d \u2014 that has demonstrated the capacity to destroy malignant cancer cells and antibiotic resistant bacteria. On a parallel track, Professor Richard Gunasekera has been demonstrating the efficacy of these same nanodrills in destroying antibiotic resistant bacteria in his new lab at Biola University where he has recently moved, along with one of Tour\u2019s former post-docs. Tour, Gunasekera, and their postdocs have published many scientific articles on the capabilities of their nanomachines in&nbsp;<em>Nature<\/em>,&nbsp;<em>American Chemical Society (ACS) Nano<\/em>, and&nbsp;<em>Nature Nanotechnology<\/em>&nbsp;Gunasekera and his team are demonstrating the ability of the nanodrills to destroy bacteria and viruses, while Tour and his team will continue to develop revolutionary applications of the nanodrills for the treatment of cancer.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Selected Publications<\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li>Ciceron Ayala-Orozco, Gang Li, Bowen Li, Vardan Vardanyan, Anatoly B. Kolomeisky, and James M. Tour, \u201c<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/adma.202309910\">How to Build Plasmon-Driven Molecular Jackhammers that Disassemble Cell Membranes and Cytoskeletons in Cancer<\/a>,\u201d <em>Advanced Materials<\/em>, 2024: 2309910 (2024).<\/li>\n\n\n\n<li>Jacob L. Beckham, Thomas S. Bradford, Ciceron Ayala-Orozco, Ana L. Santos, Dallin Arnold, Alexis R. van Venrooy, V\u00edctor Garc\u00eda-L\u00f3pez, Robert Pal, and James M. Tour, \u201c<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adma.202306669\">Distinguishing Molecular Mechanical Action from Photothermal and Photodynamic Behavior<\/a>,\u201d&nbsp;<em>Advanced Materials<\/em>, 2023: 2306669 (2023).<\/li>\n\n\n\n<li>Alexis van Venrooy, Aaron M. Wyderka, V\u00edctor Garc\u00eda-L\u00f3pez, Lawrence B. Alemany, Angel A. Mart\u00ed, and James M. Tour, \u201c<a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.joc.2c01457\">Probing the Rotary Cycle of Amine-Substituted Molecular Motors<\/a>,\u201d&nbsp;<em>Journal of Organic Chemistry<\/em>, 88 (2): 762-770 (2023).<\/li>\n\n\n\n<li>Ana L. Santos, Dongdong Liu, Anna K. Reed, Aaron M. Wyderka, Alexis van Venrooy, John T. Li, Victor D. Li, Mikita Misiura, Olga Samoylova, Jacob L. Beckham, Ciceron Ayala-Orozco, Anatoly B. Kolomeisky, Lawrence B. Alemany, Antonio Oliver, George P. Tegos, and James M. Tour, \u201c<a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.abm2055\">Light-activated molecular machines are fast-acting broad-spectrum antibacterials that target the membrane<\/a>,\u201d&nbsp;<em>Science Advances<\/em>, 8: eabm2055 (2022).<\/li>\n\n\n\n<li>Ana L. Santos, Alexis van Venrooy, Anna K. Reed, Aaron M. Wyderka, V\u00edctor Garc\u00eda-L\u00f3pez, Lawrence B. Alemany, Antonio Oliver, George P. Tegos, and James M. Tour, \u201c<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/advs.202203242\">Hemithioindigo-Based Visible Light-Activated Molecular Machines Kill Bacteria by Oxidative Damage<\/a>,\u201d&nbsp;<em>Advanced Science<\/em>, 2022 (9): 2203242 (2022).&nbsp;<\/li>\n\n\n\n<li>Richard S. Gunasekera, Thushara Galbadage, Ciceron Ayala-Orozco, Dongdong Liu, Victor Garc\u00eda-L\u00f3pez, Brian E. Troutman, Josiah J. Tour, Robert Pal, Sunil Krishnan, Jeffrey D. Cirillo, and James M. Tour, \u201c<a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acsami.9b22595\">Molecular Nanomachines Can Destroy Tissue or Kill Multicellular Eukaryotes<\/a>,\u201d&nbsp;<em>ACS Applied Materials &amp; Interfaces<\/em>, 12: 13657-13670 (2020).<\/li>\n\n\n\n<li>Thushara Galbadage, Dongdong Liu, Lawrence B. Alemany, Robert Pal, James M. Tour, Richard S. Gunasekera, and Jeffrey D. Cirillo, \u201c<a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.9b07836\">Molecular Nanomachines Disrupt Bacterial Cell Wall, Increasing Sensitivity of Extensively Drug-Resistant&nbsp;<em>Klebsiella pneumoniae<\/em>&nbsp;to Meropenem<\/a>,\u201d&nbsp;<em>ACS Nano<\/em>, 13: 14377-14387 (2019).<\/li>\n\n\n\n<li>Dongdong Liu, V\u00edctor Garc\u00eda-L\u00f3pez, Richard S. Gunasekera, Lizanne Greer Nilewski, Lawrence B. Alemany, Amir Aliyan, Tao Jin, Gufeng Wang, James M. Tour, and Robert Pal, \u201c<a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.9b01556\">Near-Infrared Light Activates Molecular Nanomachines to Drill into and Kill Cells<\/a>,\u201d&nbsp;<em>ACS Nano<\/em>, 13 (6): 6813-6823 (2019).<\/li>\n\n\n\n<li>V\u00edctor Garc\u00eda-L\u00f3pez, Fang Chen, Lizanne G. Nilewski, Guillaume Duret, Amir Aliyan, Anatoly B. Kolomeisky, Jacob T. Robinson, Gufeng Wang, Robert Pal, and James M. Tour, \u201c<a href=\"https:\/\/www.nature.com\/articles\/nature23657\">Molecular Machines Open Cell Membranes<\/a>,\u201d&nbsp;<em>Nature<\/em>, 548: 567-572 (2017).<\/li>\n\n\n\n<li>G.J. Simpson, V. Garc\u00eda-L\u00f3pez, P. Petermeier, L. Grill, and James M. Tour, \u201c<a href=\"https:\/\/www.nature.com\/articles\/nnano.2017.137\">How to build and race a fast nanocar<\/a>,\u201d&nbsp;<em>Nature Nanotechnology<\/em>, 12: 604-606 (2017).<\/li>\n\n\n\n<li>James Tour, \u201c<a href=\"https:\/\/inference-review.com\/article\/animadversions-of-a-synthetic-chemist\">Animadversions of a Synthetic Chemist<\/a>,\u201d&nbsp;<em>Inference: International Review of Science<\/em>, 2 (2) (May, 2016).<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details design-detection\"><summary>Design Detection<\/summary><center>\n<p class=\"wp-block-paragraph\">Design detection is fundamental to the theory of intelligent design, and it seeks to understand and identify the logical principles that we humans intuitively use when recognizing something was designed. This largely theoretical project arguably began in 1998 when William Dembski published his foundational peer-reviewed book with Cambridge University Press,&nbsp;<em>The Design Inference: Eliminating Chance Through Small Probabilities<\/em>,first outlining how concepts such as the explanatory filter and complex and specified information (CSI) can help us to detect design (Dembski, 1998). Dembski\u2019s follow-up work incorporated \u201cNo Free Lunch\u201d theorems and developed the Law of Conservation of Information, which hold that blind evolutionary mechanisms can shuffle CSI around, but only intelligence can generate truly novel CSI (Dembski, 2001). According to these principles, information is conserved such that \u201con average no search outperforms any other\u201d (Dembski and Marks, 2009) \u2014 meaning that even Darwinian evolution is really no better than a random search (Dembski et al. 2010; Ewert et al. 2013b). This work further shows that unless \u201cactive information\u201d is inputted by an intelligent agent to improve a search, it\u2019s effectively going to perform no better than random guessing. These researchers have applied their methodology to multiple would-be computer simulations of evolution which have been claimed to produce new information via unguided evolutionary mechanisms. In each case, their methodology identified where the programmers smuggled in \u201cactive information\u201d to make the simulation program work (Dembski and Marks 2009a; Ewert et al. 2009; Ewert et al. 2010; Ewert et al. 2012b; Ewert et al. 2012a; Ewert et al. 2013a; Ewert 2014). Additional work has developed new ways to measuring information and detect design, such as algorithmic specified complexity as an improved method of quantifying specification, which measures specification as a function of description length (Ewert et al. 2013; Ewert et al. 2015a; Ewert et al. 2015b; Dembski and Ewert 2023). This project\u2019s work is ongoing, but it has already demonstrated strong theoretical grounds to understand why only intelligence can produce new complex and specified information.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Selected Publications<\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li>William Dembski and Winston Ewert,&nbsp;<a href=\"https:\/\/www.discovery.org\/b\/the-design-inference\/\"><em>The Design Inference: Eliminating Chance through Small Probabilities<\/em><\/a>&nbsp;(2<sup>nd<\/sup>&nbsp;Edition, 2023).<\/li>\n\n\n\n<li>Eric Holloway and Robert Marks, \u201c<a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-3-319-91253-0_37\">Observation of Unbounded Novelty in Evolutionary Algorithms is Unknowable<\/a>,\u201d&nbsp;<em>In<\/em>&nbsp;Rutkowski, L., Scherer, R., Korytkowski, M., Pedrycz, W., Tadeusiewicz, R., Zurada, J. (eds)&nbsp;<em>Artificial Intelligence and Soft Computing<\/em>. ICAISC 2018.&nbsp;<em>Lecture Notes in Computer Science<\/em>, vol. 10841 (Springer, Cham, 2018).<\/li>\n\n\n\n<li>Winston Ewert, Robert J. Marks II, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2017.1\">Conservation of Information in Coevolutionary Searches<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, 2017 (1).<\/li>\n\n\n\n<li>Winston Ewert, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2015.1\">Overabundant mutations help potentiate evolution: The effect of biologically realistic mutation rates on computer models of evolution<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, Vol. 2015 (1).<\/li>\n\n\n\n<li>Winston Ewert, William A. Dembski, Robert J. Marks II, \u201c<a href=\"https:\/\/ietresearch.onlinelibrary.wiley.com\/doi\/full\/10.1049\/iet-cvi.2014.0141\">Measuring meaningful information in images: algorithmic specified complexity<\/a>,\u201d&nbsp;<em>IET Computer Vision<\/em>, Vol. 9(6): 884-894 (December, 2015).<\/li>\n\n\n\n<li>Winston Ewert, William A. Dembski and Robert J. Marks II, \u201d<a href=\"https:\/\/ieeexplore.ieee.org\/document\/6872591\/\">Algorithmic Specified Complexity in the Game of Life<\/a>,\u201d&nbsp;<em>Systems, Man, and Cybernetics: Systems, IEEE Transactions<\/em>, Vol. 45 (4): 584-594 (April, 2015).<\/li>\n\n\n\n<li>Winston Ewert, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/view\/BIO-C.2014.1\">Digital Irreducible Complexity: A Survey of Irreducible Complexity in Computer Simulations<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, Vol. 2014 (1).<\/li>\n\n\n\n<li>Winston Ewert, William A. Dembski and Robert J. Marks II, \u201c<a href=\"chrome-extension:\/\/efaidnbmnnnibpcajpcglclefindmkaj\/https:\/robertmarks.org\/REPRINTS\/2013_OnTheImprobabilityOfAlgorithmicSpecifiedComplexity.pdf\">On the Improbability of Algorithmically Specified Complexity<\/a>,\u201d&nbsp;<em>Proceedings of the 2013 IEEE 45<sup>th<\/sup>&nbsp;Southeastern Symposium on Systems Theory (SSST), Baylor University, March 11, 2013<\/em>, pp. 68-70.<\/li>\n\n\n\n<li>Winston Ewert, William A. Dembski, Robert J. Marks II, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/view\/BIO-C.2013.4\">Active Information in Metabiology<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, Vol. 2013 (4).<\/li>\n\n\n\n<li>Winston Ewert, W. A. Dembski and Robert J. Marks II, \u201c<a href=\"https:\/\/ieeexplore.ieee.org\/document\/6524963\">Conservation of Information in Relative Search Performance<\/a>,\u201d&nbsp;<em>Proceedings of the 2013 IEEE 45<sup>th<\/sup>&nbsp;Southeastern Symposium on Systems Theory, Baylor University, March 11, 2013<\/em>, pp. 41-50.<\/li>\n\n\n\n<li>Winston Ewert, William A. Dembski, Ann K. Gauger, Robert J. Marks II, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/view\/BIO-C.2012.4\">Time and Information in Evolution<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, 2012 (4).<\/li>\n\n\n\n<li>Winston Ewert, W. A. Dembski and Robert J. Marks II, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/view\/BIO-C.2012.1\">Climbing the Steiner Tree \u2014Sources of Active Information in a Genetic Algorithm for Solving the Euclidean Steiner Tree Problem<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, 2012 (1).<\/li>\n\n\n\n<li>William A. Dembski and Robert J. Marks II, \u201c<a href=\"https:\/\/www.fujipress.jp\/jaciii\/jc\/jacii001400050475\/\">The Search for a Search: Measuring the Information Cost of Higher Level Search<\/a>,\u201d&nbsp;<em>Journal of Advanced Computational Intelligence and Intelligent Informatics<\/em>, Vol. 14 (5):475-486 (2010).<\/li>\n\n\n\n<li>Winston Ewert, George Monta\u00f1ez, William Dembski and Robert J. Marks II, \u201c<a href=\"https:\/\/ieeexplore.ieee.org\/xpl\/conhome\/5439160\/proceeding\">Efficient Per Query Information Extraction from a Hamming Oracle<\/a>,\u201d&nbsp;<em>42nd South Eastern Symposium on System Theory<\/em>, pp. 290-297 (March, 2010).<\/li>\n\n\n\n<li>Winston Ewert, William Dembski and Robert J. Marks II, \u201c<a href=\"https:\/\/ieeexplore.ieee.org\/document\/5345941\">Evolutionary Synthesis of Nand Logic: Dissecting a Digital Organism<\/a>,\u201d&nbsp;<em>Proceedings of the 2009 IEEE International Conference on Systems, Man, and Cybernetics<\/em>, pp. 3047-3053 (Oct., 2009).<\/li>\n\n\n\n<li>William A. Dembski and Robert J. Marks II, \u201c<a href=\"https:\/\/ieeexplore.ieee.org\/document\/5346119\">Bernoulli\u2019s Principle of Insufficient Reason and Conservation of Information in Computer Search<\/a>,\u201d&nbsp;<em>Proceedings of the2009 IEEE International Conference on Systems, Man, and Cybernetics<\/em>, pp. 2647-2652 (Oct., 2009b).<\/li>\n\n\n\n<li>William A. Dembski and Robert J. Marks II, \u201c<a href=\"https:\/\/ieeexplore.ieee.org\/document\/5204206\">Conservation of Information in Search: Measuring the Cost of Success<\/a>,\u201d&nbsp;<em>IEEE Transactions on Systems, Man, and Cybernetics-Part A: Systems and Humans<\/em>, 39 (5): 1051-1061 (Sept., 2009a).<\/li>\n\n\n\n<li>William Dembski,&nbsp;<a href=\"https:\/\/www.discovery.org\/b\/no-free-lunch\/\"><em>Why Specified Complexity Cannot Be Purchased without Intelligence<\/em><\/a>&nbsp;(Rowman &amp; Littlefield, 2001).<\/li>\n\n\n\n<li>William A. Dembski,&nbsp;<em>The Design Inference: Eliminating Chance through Small Probabilities<\/em>&nbsp;(Cambridge: Cambridge University Press, 1998).<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details design-systematics\"><summary>Design and Systematics<\/summary><center>\n<p class=\"wp-block-paragraph\">Intelligent design is not necessarily incompatible with common ancestry, but it may suggest non-materialistic possibilities could lead to new insights into systematics, the study of how organisms are related. This project is exploring whether dependency graphs can better explain how organisms are related compared to nested hierarchies, which are predicted by common ancestry. Dependency graphs allow the idea of \u201ccommon design\u201d to be applied to systematics, where organisms share similar traits not necessarily because they were inherited from a common ancestor but because they were designed using similar blueprints. When organisms that are \u201cdistantly related\u201d nonetheless share similar parts or genetic modules, common design might be a superior explanation to common descent. Various papers produced by this project are exploring the use of dependency graphs to test the idea of common design against common ancestry.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Selected Publications<\/strong><\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li><em> <\/em>Winston Ewert, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2023.1\">AminoGraph Analysis of the Auditory Protein Prestin From Bats and Whales Reveals a Dependency-Graph Signal That Is Missed by the Standard Convergence Model<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, 2023 (1): 1-15 (2023).<\/li>\n\n\n\n<li>Winston Ewert, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2018.3\">The Dependency Graph of Life<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, 2018 (1): 1-27 (2018).<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details human-origins\"><summary>Human Origins<\/summary><center>\n<p class=\"wp-block-paragraph\">A major area where evolution interfaces with traditional beliefs is human origins. For example, evolutionists have claimed that human genetic diversity is so great that humanity could never have derived from an initial pair of two individuals, but instead evolved from a population of thousands. They have also claimed that humans are not exceptional and have no biological or cognitive features that distinguish them from other animals. The Human Origins project is testing these claims. A rigorous population genetics model, developed by mathematician Ola H\u00f6ssjer and geneticist Ann Gauger, was applied to a database of thousands of sequenced human genomes. The results showed that it was indeed possible for humanity to have originated from some original pair. Another aspect of this project is comparing humans and chimps to determine what distinguishes the two species.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Selected Publications<\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li>Ola H\u00f6ssjer and Ann K. Gauger, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/view\/BIO-C.2019.1\">A Single-Couple Human Origin is Possible<\/a>,\u201d<em>&nbsp;BIO-Complexity<\/em>, 2019 (1): 1-20 (2019).<\/li>\n\n\n\n<li>Ola H\u00f6ssjer, Ann K. Gauger, Colin Reeves, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/view\/BIO-C.2016.3\">Genetic Modeling of Human History, Part 1: Comparison of Common Descent and Unique Origin Approaches<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, 2016 (3): 1-15 (2016).<\/li>\n\n\n\n<li>Ola H\u00f6ssjer, Ann K. Gauger, Colin Reeves, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2016.4\">Genetic Modeling of Human History, Part 2: A Unique Origin Algorithm<\/a>,\u201d&nbsp;<em>BIO-Complexity<\/em>, 2016 (4): 1-36 (2016).&nbsp;<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details engineering\"><summary>Engineering Research Group<\/summary><center>\n<p class=\"wp-block-paragraph\">The Engineering Research Group (ERG) is a consortium of over 100 engineers and biologists who are working together under the assumption that viewing biological systems are engineered can help us to better understand how biological systems operate. The ERGs goals are (1) apply engineering principles to better understand biological systems, (2) craft a design-based theoretical framework that explains and predicts the behaviors of living systems, and (3) develop research programs that demonstrate the engineering principles at work in living systems. Workgroups and researchers within this project are looking at topics such as Mechanisms of Adaptation, Viral Origins, Modeling Biochemical Pathways and Molecular Machines, Biomimetics, Biological Signaling, and the Origin of Life. One key participant in this project is Bristol University engineering professor Stuart Burgess, who has critically investigated claims of poor-design in the human body and shown the accusations are false. The group hosts a bi-annual Conference on Engineering in Living Systems (CELS) where participants convene to present their ideas and results.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Selected Publications<\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li>James D. Johansen, \u201c<a href=\"https:\/\/incose.onlinelibrary.wiley.com\/doi\/10.1002\/sys.21752?af=R\">Bacterial chemotaxis control process analysis with SysML<\/a>,\u201d <em>Systems Engineering<\/em>, 2024: 1-23 (2024).<\/li>\n\n\n\n<li>Stuart Burgess, Alex Beeston, Joshua Carr, Kallia Siempou, Maya Simmonds, and Yasmin Zanker, \u201c<a href=\"https:\/\/www.mdpi.com\/2313-7673\/8\/6\/455\">A Bio-Inspired Arched Foot with Individual Toe Joints and Plantar Fascia<\/a>,\u201d <em>Biomimetics<\/em>, 8: 455 (2023).<\/li>\n\n\n\n<li>Stuart Burgess, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/view\/BIO-C.2022.3\">Why the Ankle-Foot Complex Is a Masterpiece of Engineering and a Rebuttal of \u2018Bad Design\u2019 Arguments<\/a>,\u201d <em>BIO-Complexity<\/em>, 2022 (3): 1-10 (2022).<\/li>\n\n\n\n<li>Waldean A. Schulz, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2021.1\">An Engineering Perspective on the Bacterial Flagellum: Part 1\u2014Constructive View<\/a>,\u201d <em>BIO-Complexity<\/em>, 2021 (1): 1-14 (2021).<\/li>\n\n\n\n<li>Waldean A. Schulz, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2021.2\">An Engineering Perspective on the Bacterial Flagellum: Part 2\u2014Analytic View<\/a>,\u201d <em>BIO-Complexity<\/em>, 2021 (2): 1-16 (2021).<\/li>\n\n\n\n<li>Waldean A. Schulz, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2021.3\">An Engineering Perspective on the Bacterial Flagellum: Part 3\u2014Observations<\/a>,\u201d <em>BIO-Complexity<\/em>, 2021 (3): 1-7 (2021).<\/li>\n\n\n\n<li>Stuart Burgess, \u201c<a href=\"https:\/\/iopscience.iop.org\/article\/10.1088\/1748-3190\/abf744\">A review of linkage mechanisms in animal joints and related bioinspired designs<\/a>,\u201d <em>Bioinspiration &amp; Biomimetics<\/em>, 16: 041001 (2021).<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details flagellar-evolution\"><summary>Flagellar Evolution<\/summary><center>\n<p class=\"wp-block-paragraph\">The bacterial flagellum is a prime example of a complex molecular machine which seemingly challenges step-by-step Darwinian models of evolution. The flagellar evolution project seeks to investigate bacterial flagellar proteins to determine if homologues exist in other biological systems. This has the potential to test the co-option argument which claims that flagellar proteins were borrowed or \u201cco-opted\u201d from these other systems. Another important aspect of this project is directly testing for irreducible complexity of the flagellum through genetic knockout experiments. Dustin Van Hofwegen, Assistant Professor of Biology &amp; Biochemistry at University of Northwestern, St. Paul, is doing genetic knockout experiments on the flagellum to determine what genes compose its irreducibly complex core.<\/p>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details junk-dna-function\"><summary>Junk DNA Workgroup<\/summary><center>\n<p class=\"wp-block-paragraph\">Evolutionary scientists have long-claimed that the vast majority of our DNA which does not code for proteins is useless genetic \u201cjunk.\u201d Intelligent design theorists, on the other hand, have long-predicted that much of this non-protein-coding DNA likely has important biological functions. This prediction flows naturally out of the fact that intelligent agents typically design things with function and for a purpose. Because of this ID prediction, quite a few ID proponents have been involved in research investigating function for non-protein-coding DNA\u2014what was previously considered \u201cjunk.\u201d Many of these scientists are part of our Junk DNA Workgroup, a collaboration of scientists who are seeking function for \u201cjunk DNA.\u201d Many of these researchers are in sensitive positions so we do not list their names or publications.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Selected <\/strong>Publications<\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li>Richard Sternberg, \u201cOn the Roles of Repetitive DNA Elements in the Context of a Unified Genomic- Epigenetic System,\u201d <em>Annals of the New York Academy of Sciences<\/em>, 981: 154-188 (2002).<\/li>\n\n\n\n<li>Richard Sternberg and James A. Shapiro, \u201cHow repeated retroelements format genome function,\u201d <em>Cytogenetic and Genome Research<\/em>, 110: 108-116 (2005).<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details mind-body-workgroup\"><summary>Mind-Body Workgroup<\/summary><center>\n<p class=\"wp-block-paragraph\">The mind-body workgroup is a team of scientists and scholars brought together by Discovery Institute\u2019s&nbsp;<a href=\"https:\/\/bradley.center\/\">Bradley Center for Natural and Artificial Intelligence<\/a>&nbsp;who have expertise in issues related to brain function, consciousness, and philosophy of mind. In 2023 they produced a technical volume,&nbsp;<a href=\"https:\/\/www.amazon.com\/Minding-Brain-Information-Empirical-Science\/dp\/163712029X\"><em>Minding the Brain: Models of the Mind, Information, and Empirical Science<\/em><\/a>, edited by philosopher Angus Menuge, computer scientist Robert Marks, and software engineer Brian Krouse. Their ongoing work is evaluating whether the mind can be reduced to the brain or whether consciousness can exist apart from the brain.&nbsp;<\/p>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details orphan-genes\"><summary>Orphan Genes<\/summary><center>\n<p class=\"wp-block-paragraph\">Evolutionists had long believed that most genes originated from ancestral genes duplicating and then evolving into new genes with new functions. Genes originating from random DNA sequences was considered too difficult due to the rarity of functional proteins and to other challenges. However, over the past few decades geneticists have identified large numbers of genes which have no discernable similarity to any identified genes outside of a particular genus or even species. These taxonomically restricted or orphan genes can often make up more than 10% of genes in a given species, and they are believed to have originated de novo from random sequences of DNA. This abundance of orphans poses an enormous challenge to undirected evolutionary models, since it implies that large amounts of new genetic information constantly appeared throughout life in very short amounts of time. (Orphan genes are sometimes called ORFan genes, alluding to the term ORF which refers to an \u201cOpen Reading Frame\u201d which defines a gene.) A team of scientists and computer programmers headed by Richard Gunasekera and Paul Nelson are developing a web-based tool known as ORFanID which will allow researchers to directly enter new gene sequences and graphically display which other species or higher groups possess the identified gene. This tool will accelerate the identification of orphan genes, and it will help determine their distribution in different animal groups.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Selected Publications<\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li>Richard S. Gunasekera, Komal K. B. Raja, Suresh Hewapathirana, Emanuel Tundrea, Vinodh Gunasekera, Thushara Galbadage, Paul A. Nelson, \u201c<a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0291260\">ORFanID: A web-based search engine for the discovery and identification of orphan and taxonomically restricted genes<\/a>,\u201d&nbsp;<em>PLOS One<\/em>, 18(10): e0291260 (2023).&nbsp;<\/li>\n\n\n\n<li>Nelson, P.A.; and Buggs, R.J.A., \u201c<a href=\"https:\/\/www.cambridge.org\/core\/books\/abs\/next-generation-systematics\/next-generation-apomorphy-the-ubiquity-of-taxonomically-restricted-genes\/067A152B98574BA62A9F1373FF04CD0A\">Next Generation Apomorphy: The Ubiquity of Taxonomically Restricted Genes<\/a>,\u201d in&nbsp;<em>Next Generation Systematics<\/em>, ed. Peter D. Olson, Joseph Hughes, and James A. Cotton (Cambridge: Cambridge University Press, 2016), pp. 237\u2013263.<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details plants-cancer\"><summary>Plants and Cancer<\/summary><center>\n<p class=\"wp-block-paragraph\">If life was designed, could some species be specially designed to provide medical benefits to humans? Richard Gunasekera, Research Professor of Science, Technology and Health at Biola University, has predicted that plants will have special molecules that are designed to fight cancer. Evolution has no reason to expect this, but under a design-based view of biology, it makes perfect sense. He has developed techniques to screen plant samples for the relevant biomolecules and test their efficacy in targeting cancer cell lines. This research is currently in early phases.<\/p>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details protein-origins\"><summary>Protein Origins and \u201cProtein Zoo\u201d<\/summary><center>\n<p class=\"wp-block-paragraph\">This longstanding project aims to assess the evolvability of various types of proteins through experimental and computational research. This foundational ID research was first conducted by Douglas Axe at the Centre for Protein Engineering (CPE) in Cambridge, and published in 2000 and 2004 in the&nbsp;<em>Journal of Molecular Biology<\/em>. It showed that only 1 in 10<sup>77<\/sup>&nbsp;sequences could yield a stable protein fold that could yield a functional beta-lactamase enzyme. Follow-up research by Axe (2010) performed a population genetics study which found that when a feature requires more than six mutations before giving any benefit, this feature is unlikely to arise in the whole history of the Earth \u2014 even in the case of bacteria that have large population sizes and rapid generation times. Additional research by Gauger and Axe (2011) found that merely converting a particular metabolic enzyme to perform the function of a closely related enzyme \u2014 the kind of conversion that evolutionists claim can readily happen \u2014 would require a minimum of seven mutations. Yet this exceeds the limits of what Darwinian evolution can produce over the Earth\u2019s entire history, as calculated by Axe (2010). A follow-up study by Gauger, Axe, and biologist Mariclair Reeves bolstered this finding by attempting to mutate additional enzymes to perform the function of a closely related protein (Reeves et al. 2014). After inducing all possible single mutations in the enzymes, and many other combinations of mutations, they found that evolving a protein to perform the function of a closely related protein would take over 10<sup>15<\/sup>&nbsp;years \u2014 over 100,000 times longer than the age of the Earth. Collectively, this research indicates strong barriers to protein evolution, and that evolving a protein from a similar protein often requires more time (and mutations) than is available. The project is currently headed by Brian Miller\u2014and also includes Ann Gauger, Douglas Axe, Marci Reeves, and Paul Nelson. It is now investigating whether functional sequence rarity entails isolation in sequence space (thereby inaccessible to mutation-selection), and also to catalog the spectrum of broad types of proteins to determine which types might be evolvable by mutation and selection, and which are not. This refers to the \u201cprotein zoo\u201d \u2014 the idea that there are lots of types of proteins which exist. This project aims to catalog many of these types of proteins and ask whether some are evolvable by natural mechanisms, while others are not.&nbsp;<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Selected Publications<\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li>Mariclair A. Reeves, Ann K. Gauger, and Douglas D. Axe, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2014.4\">Enzyme Families\u2013Shared Evolutionary History or Shared Design? A Study of the GABA-Aminotransferase Family<\/a>,\u201d <em>BIO-Complexity<\/em>, 2014: 1-16 (2014).&nbsp;<\/li>\n\n\n\n<li>Ann K. Gauger and Douglas D. Axe. \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2011.1\">The Evolutionary Accessibility of New Enzyme Functions: A Case Study from the Biotin Pathway<\/a>,\u201d <em>BIO-Complexity<\/em>, 2011: 1-17 (2011).&nbsp;<\/li>\n\n\n\n<li>Ann K. Gauger, Stephanie Ebnet, Pamela F. Fahey, and Ralph Seelke, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2010.2\">Reductive Evolution Can Prevent Populations from Taking Simple Adaptive Paths to High Fitness<\/a>,\u201d <em>BIO-Complexity<\/em>, 2010: 1-9 (2010).&nbsp;<\/li>\n\n\n\n<li>Douglas D. Axe, \u201c<a href=\"https:\/\/bio-complexity.org\/ojs\/index.php\/main\/article\/viewArticle\/BIO-C.2010.4\">The Limits of Complex Adaptation: An Analysis Based on a Simple Model of Structured Bacterial Populations<\/a>,\u201d \u201c<em>BIO-Complexity<\/em>, 2010: 1\u201310 (2010).&nbsp;<\/li>\n\n\n\n<li>Douglas D. Axe, Brendan W. Dixon, and Philip Lu, \u201c<a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0002246\">Stylus: A System for Evolutionary Experimentation Based on a Protein\/Proteome Model with Non-Arbitrary Functional Constraints<\/a>,\u201d <em>PLoS One<\/em>, 3(6): e2246 (2008).&nbsp;<\/li>\n\n\n\n<li>Douglas D. Axe, \u201c<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0022283604007624\">Estimating the Prevalence of Protein Sequences Adopting Functional Enzyme Folds<\/a>,\u201d <em>Journal of Molecular Biology<\/em>, 341: 1295\u2013315 (2004).&nbsp;<\/li>\n\n\n\n<li>Douglas D. Axe, \u201c<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0022283600939974\">Extreme Functional Sensitivity to Conservative Amino Acid Changes on Enzyme Exteriors<\/a>,\u201d <em>Journal of Molecular Biology<\/em>, 301: 585\u2013595 (2000).&nbsp;<\/li>\n<\/ul>\n<\/center><\/details>\n\n\n\n<details class=\"wp-block-signal-details waiting-times\"><summary>Waiting Times<\/summary><center>\n<p class=\"wp-block-paragraph\">This team of researchers \u2014 including biologists Richard Sternberg and Ann Gauger, mathematician Ola H\u00f6ssjer, and headed by paleontologist G\u00fcnter Bechly \u2014 is evaluating whether geologically available windows of time can accommodate the waiting times for the required mutations build the complex anatomical features that appear throughout the history of life. In 2018, these investigators published a theoretical mathematical model for making these assessments in Springer Proceedings in Mathematics and Statistics, and in 2021 they further developed their mathematical model in a paper published in&nbsp;<em>Journal of Theoretical Biology<\/em>. They are now applying their model to various systems.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Selected Publications<\/h4>\n\n\n\n<ul class=\"wp-block-list dotted-lines\">\n<li>Ola H\u00f6ssjer, Gu\u0308nter Bechly and Ann Gauger. (2021), \u201c<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022519321000795\">On the waiting time until coordinated mutations get fixed in regulatory sequences<\/a>,\u201d&nbsp;<em>Journal of Theoretical Biology<\/em>, 524 (2021): 110657.<\/li>\n\n\n\n<li>Ann Gauger, see H\u00f6ssjer, O., Bechly, G. and Gauger, A. (2018), \u201c<a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-3-030-02825-1_12\">Phase-type distribution approximations of the waiting time until coordinated mutations get fixed in a population<\/a>,\u201d chapter 12 in&nbsp;<em>Stochastic Processes and Algebraic Structures \u2014 From Theory Towards Applications. Volume 1: Stochastic processes and Applications<\/em>, S. Silvestrov, A. Malyarenko, and M.Ran\u010di\u0107 (eds.), Springer Proceedings in Mathematics and Statistics, pp. 245-313.<\/li>\n<\/ul>\n<\/center><\/details>\n<\/center>\n<\/section>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity constrain-lg research-divider display-none\"\/>\n\n\n\n<section class=\"wp-block-signal-section researchers constrain-xl m-t-n\">\n<div class=\"wp-block-cover is-light has-custom-content-position is-position-bottom-center researchers has-white-color has-text-color has-link-color wp-elements-2\" style=\"min-height:200px;aspect-ratio:unset;\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1928\" class=\"wp-block-cover__image-background wp-image-10662\" alt=\"Scientists, Environmentalists, Engineers, deliberating geoengineering at the North Pole 3D render, overcast, vignette, Silhouette shot\" src=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/silhouettes-clouds-scaled.jpg\" data-object-fit=\"cover\" srcset=\"https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/silhouettes-clouds-scaled.jpg 2560w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/silhouettes-clouds-1000x753.jpg 1000w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/silhouettes-clouds-1600x1205.jpg 1600w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/silhouettes-clouds-768x578.jpg 768w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/silhouettes-clouds-1536x1157.jpg 1536w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/silhouettes-clouds-2048x1543.jpg 2048w, https:\/\/www.discovery.org\/m\/sites\/11\/2024\/05\/silhouettes-clouds-50x38.jpg 50w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><small class=\"description toggler\"><span>Image licensed via Adobe Stock<\/span><\/small><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim\" style=\"background-color:#748392\"><\/span><div class=\"wp-block-cover__inner-container is-layout-constrained wp-block-cover-is-layout-constrained\">\n<header class=\"wp-block-signal-header constrain-md\">\n<h2 class=\"wp-block-heading\" id=\"researchers\">Highlighted Researchers<\/h2>\n<\/header>\n<\/div><\/div>\n\n\n\n<center class=\"wp-block-signal-center\">\n<p class=\"constrain-md wp-block-paragraph\">Below is a non-exhaustive list of select researchers involved in the ID 3.0 research program. (Note: Some researchers involved in ID 3.0 projects must remain anonymous due to the threat of potential harm to their careers.)<\/p>\n\n\n<span class=\"hailed-persons \" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><mark id=\"259\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"323\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"522\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"171\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"380\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"260\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"364\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"255\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"172\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"473\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"504\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"101\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"490\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"161\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"262\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"205\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"181\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"465\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"578\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"241\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><mark id=\"479\" class=\"hailed tease  has-description\" data-frequency=\"https:\/\/www.discovery.org\/wp-json\/signal\/persons?&person=agauger,rgunasekera,smeyer,ereeves,meberlin,dvanhofwegen,mreeves,daxe,sburgess,ohossjer,gbechly,rsternberg,megnor,wdembski,wewert,sminnich,ggonzalez,pnelson,bmiller,jmclatchie,cluskin&format=span&show-projects=1&show-education=1&refresh=600\" refresh-needed=\"1\" echo-since=\"2341\"><\/mark><\/span>\n<\/center>\n<\/section>\n\n\n\n<script>document.querySelector('address[data-person=\"gbechly\"] h3 a').textContent = 'Gunter Bechly (1963-2025)';<\/script>\n","protected":false},"excerpt":{"rendered":"<p>25+ Active Research Projects 250+ Peer-Reviewed Papers $10+ million total budget since 2016<\/p>\n","protected":false},"author":295,"featured_media":10510,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"wholes\/center.php","meta":{"_acf_changed":false,"inline_featured_image":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","footnotes":""},"categories":[],"tags":[303,304],"class_list":["post-10504","page","type-page","status-publish","has-post-thumbnail","hentry","tag-constrain-lg","tag-float-header"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.discovery.org\/id\/wp-json\/wp\/v2\/pages\/10504","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.discovery.org\/id\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.discovery.org\/id\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.discovery.org\/id\/wp-json\/wp\/v2\/users\/295"}],"replies":[{"embeddable":true,"href":"https:\/\/www.discovery.org\/id\/wp-json\/wp\/v2\/comments?post=10504"}],"version-history":[{"count":0,"href":"https:\/\/www.discovery.org\/id\/wp-json\/wp\/v2\/pages\/10504\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.discovery.org\/id\/wp-json\/wp\/v2\/media\/10510"}],"wp:attachment":[{"href":"https:\/\/www.discovery.org\/id\/wp-json\/wp\/v2\/media?parent=10504"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.discovery.org\/id\/wp-json\/wp\/v2\/categories?post=10504"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.discovery.org\/id\/wp-json\/wp\/v2\/tags?post=10504"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}